Reglan Medication And Tardive Dyskinesia
Reglan Medication And Tardive Dyskinesia
The Reglan drug, also known by the generic name “metoclopramide”, was first approved by the FDA in 1980. It is currently available in several different forms in both the branded “Reglan” and generic “metoclopramide” products. Reglan is primarily prescribed for gastroesophageal reflux (GER) and gastroesphageal reflux disease (GERD) and diabetic gastroparesis. The U.S. Food and Drug Administration (FDA) announced in February 2009 that manufacturers of metoclopramide are required to add a black box warning to their packaging alerting consumers about the risk of tardive dyskinesia associated with its long-term and/or high-dose use.
Reglan is prescribed for both adults and children depending on the treatment. The drug is used for several different therapies including:
• Acid reflux
• GERD (gastroesphageal reflux disease)
• Diabetic gatroparesis
• Nausea from migraines and following surgery
• Breastfeeding mothers – increase milk production
Metoclopramide is available in a variety of forms including tablets, syrups and injections. Products that contain metoclopramide include Reglan Tablets, Reglan Oral Disintegrating Tablets, Metoclopramide Oral Solution and Reglan Injection. Over 2 million Americans have been prescribed Reglan.
Recent studies suggest that (metoclopramide) Reglan tardive dyskinesia side effects are directly related to patients who used metoclopramide for longer than three months. In one study that the FDA analyzed, around 20 percent of patients who used metoclopramide took it for longer than three months.
Reglan and generic metoclopramide are now also commonly prescribed for the treatment of gastrointestinal disorders like acid reflux and GERD along with treatment for nausea and therapy for nursing mothers to help increase milk production. More than two million Americans use these products including infants and children. Tardive dyskinesia is characterized by repetitive, involuntary, purposeless movements including movements of the fingers, arms, legs, rapid eye blinking and lip smacking.
Tardive dyskinesia (TD) is a drug-induced movement disorder caused by the long-term use of neuroleptic drugs. Tardive means “delayed” and dyskinesia means “abnormal movement.” Th
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is serious neurological syndrome is often irreversible and may become permanent. Since the 1950’s a family of drugs referred to as dopamine receptor blocking drugs (DRB) have been prescribed for certain mental health conditions and are now also commonly prescribed for the treatment of GERD and nausea.
Tardive Dyskinesia Symptoms
• Facial grimacing
• Repetitive chewing
• Jaw swinging
• Tongue thrusting
There is no standard treatment for patients faced with a tardive dyskinesia diagnosis and treatment is highly individualized. Several different treatments are available to help reduce the frequency of muscle spasms and pain:
• Medication – helps correct imbalances in neurotransmitters
• Botulinum toxin injections (Botox) – stops muscle spasms by blocking release of the neurotransmitter acetylcholine
• Deep brain stimulation (DBS) – electrical stimulation is passed into the brain through electrodes to targeted areas that control movement interrupting the brain’s faulty signals
• Speech / physical therapy
By: John1 Whitney1
Article Directory: http://www.articledashboard.com
Steve Fields is author of this article on Reglan Lawsuit.
Find more information about Reglan Side Effects here.
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